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There is some evidence, at the proximate level, that breastfeeding activates tumor immune response, but such findings are complicated by categorical measures of breastfeeding (e.g., presence/absence of any reported breastfeeding) 29

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Our experiments have elucidated a coordinated mechanism underlying this phenomenon, characterized by the rapid induction of ISR and oxidative stress response (OSR), accompanied by increased GDF15 and FGF21, and a reduction in CoA levels resulting in metabolic inefficiency, therefore offering insights for potential intervention in metabolic diseases and body-weight control

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[DOI] [PMC free article] [PubMed] [Google Scholar] de Simone A, Hubbard R, de la Torre NV, Velappan Y, Wilson M, Considine MJ, Soppe WJJ, Foyer CH

GSCs #1 and #163 were therefore treated with: (i) Z-VAD-FMK, an inhibitor of caspase-dependent apoptosis