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American Journal of Medical Genetics Part B: Neuropsychiatric Genetics

Beiersdorf J, Hevesi Z, Calvigionin D, Pyszkowski J, Romanov R, Szodorai E, et al

c-Myc directly activates the genes involved in nucleotide synthesis, including thymidylate synthase for pyrimidine metabolism, inosine monophosphate dehydrogenase 1 and 2 for purine metabolism, and phosphoribosyl pyrophosphate (PRPP) synthetase 2 for the production of PRPP, which is a common precursor for purine and pyrimidine nucleotides

JN: Formal Analysis, Writing review and editing, Software

Rosacea patients are believed to have an over-growth of skin microorganisms called Demodex folliculorum, contributing to skin hypersensitivity

[12] The subsequent steps ultimately lead to the synthesis of UDP-N-acetylglucosamine (UDP-GlcNAc), which is used in both N -linked and O -linked glycosylation of proteins, lipids, and nucleic acids