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This mutated NOTCH1 is characterized by an extended half-life of the NICD, prolonged NF-B activity, and sustained transcription of genes involved in cell survival and proliferation [15,16,17,18]

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10.1371/journal.pone.0112357 136

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Contrariwise, EAAT-2/GLT-1 is not detected in rat brains early after birth, and its expression maximizes within 3 to 5 weeks of age [43,44,45]

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Its intracellular concentration equals from 1 to 15 mM [27,28]

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, & Rabinkov, A

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Palmitoyl Dipeptide Peptide that improves collagen production and strengthens the dermal epidermal junction (DEJ) to improve skins structural strength

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