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Am J Physiol Endocrinol Metab 314: E572E583

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If an athlete is prescribed a GLP-1 by a doctor to manage Type 2 diabetes, it's important to be aware of the potential for Relative Energy Deficiency in Sport (REDs) due to under-fueling, so your athlete should be working with their doctor and other professionals to determine appropriate fueling and training while using the medication

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However, oral weight-loss medications do exist: oral Wegovy (semaglutide) was approved in late 2025, and Foundayo (orforglipron), an oral GLP-1 pill from Eli Lilly, was FDA-approved in April 2026