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In fact, it has been previously suggested that the deficiency of endogenous GSH as a whole is reflective of a significant factor for the pathogenesis of various diseases through mechanisms involving oxidative stress and inflammation

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Hasan R, Humphrey J, Bettencourt C, Newcombe J, Lashley T, Fratta P, Raj T (2022) Transcriptomic analysis of frontotemporal lobar degeneration with TDP-43 pathology reveals cellular alterations across multiple brain regions

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This comprehensive review examines the development status, clinical efficacy, and safety profile of DPP1 inhibitors in neutrophil-driven diseases, particularly non-cystic fibrosis bronchiectasis (NCFBE) and chronic obstructive pulmonary disease (COPD)