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Translational studies using exosomes showed a relationship between the epigenetic modulation of glutamatergic function and a brain metabolic dysfunction known as insulin resistance (IR) as showed by an increase and sex-specific phosphorylation in the expression of IRS1, a key marker of the insulin signaling cascade, in discrete exosomes enriched for the neural cell adhesion molecule L1 (L1CAM), a protein highly expressed in the brain [52, 70,71,72]

Effect of Vacuum Impregnated Fish Gelatin and Grape Seed Extract on Metabolite Profiles of tilapia ( Oreochromis niloticus ) Fillets during Storage

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Treatment with L-carnitine ameliorated symptoms of encephalopathy subsequent to long term use of valproate [79], and the antibiotic cefditoren pivoxil [80]

470,471 Impaired vagal nerve function exacerbates gastrointestinal symptoms

doi: 10.3164/jcbn.12-122 49 KimSHKimSHLeeJHLeeBHYoonHJShinDHet al