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The clinical relevance is straightforward

Some algae and plants have an NADPH-independent thioredoxin reductase that, instead, obtains reducing power directly from the electron transport chain of the photosynthesis light-reaction

doi: 10.1016/j.intimp.2020.106909 [DOI] [PubMed] [Google Scholar] 223.Faust HJ, Zhang H, Han J, et al

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Glycation-induced inactivation of antioxidant enzymes and modulation of cellular redox status in lens cells

Instead, he suggests non-permanent fillers that can be more easily dissolved, like Restylane-L or Belotero
