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Summary: While early studies found evidence of modest benefit, later and larger studies failed to find ALCAR effective for established dementia [15]

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This is potentially linked to increased levels of a compound called TMAO in the blood [14]

There is a strong correlation between hepatic encephalopathy and abnormal ammonia handling, and ALC has been shown to induce ureagenesis leading to decreased blood and brain ammonia levels [60]

Applied Food Sciences UAS MAS Nutrition & Health ETHZ

doi: 10.1002/jnr.490200413 [DOI] [PubMed] [Google Scholar] 6.Fernandez E, Pallini R, Gangitano C, et al