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Directions for Use: Administer by intramuscular, subcutaneous or intravenous injection, 2 to 4 g per kg of body weight

There is no solid proof that B12 shots cause weight loss in people who are not deficient

Kass et al., 1993

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Dermatological reactions represent the most consistently documented side effect of excessive B12 intake

Oral administration to diet-induced-obese mice for ~10 days reduces fat mass without altering food intake, decreases adipocyte size, restores insulin sensitivity, and increases adipose NAD and SAM levels [2]