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[DOI] [PMC free article] [PubMed] [Google Scholar] 40.Perry S.W., Norman J.P., Barbieri J., Brown E.B., Gelbard H.A

Nonpharmacological treatments for pain include physical therapy, acupuncture, and other forms of psychotherapy to help manage symptoms

To avoid the deleterious effects of high doses of therapeutic drugs on macrophages, drugs can be loaded into liposomes or nanoparticles to enhance their stability, and DOX-loaded PLGA nanoparticles [72] and 7-ethyl-10-hydroxycamptothecin (SN38) nanoparticles [73] delivered by macrophages have shown good antitumor effects

PMID 10654958

Distribution of cystine/glutamate exchange transporter, system x(c)-, in the mouse brain