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[ref][ref] Rare mutations in CPT2 cause carnitine palmitoyltransferase II (CPT II) deficiency

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The second product of PLC action on PIP 2 , IP 3 is a small water-soluble molecule, which diffuses away from the membrane, and through the cytosol to bind to IP 3 receptors on the endoplasmic reticulum inducing the release of Ca 2+ from intracellular stores found within the organelle [4]