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& Rodriguez, J

doi: 10.1016/j.freeradbiomed.2018.06.024

The biochemical mechanisms of ferroptosis involve a complex interaction between oxidative stress, lipid metabolism, and iron homeostasis that results in the peroxidation of polyunsaturated fatty acid (PUFA)-containing phospholipids to produce phospholipid peroxide radicals

While exact timelines are still being studied, it may remain active for several hours and potentially stay in the body for up to a couple of days

Advanced formulations utilizing GE11 peptide-conjugated chitosan nanoparticles can specifically target EGFR-overexpressing triple-negative breast cancer cells, leading to the downregulation of miR-21 and inhibition of the AKT/ERK signaling axis (147)

Mechanisms of estrogen action
