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Exercise performance Intensive or prolonged exercise can result in excessive production of ROS and oxidative damage in muscles

& Manson, J.E., 2002

Nutrition and bone health: turning knowledge and beliefs into healthy behaviour

doi: 10.1016/j.juro.2013.05.022

Peroxisomal -oxidation is incomplete and is responsible for the oxidation of very long-chain fatty acids (VLCFAs) and branched-chain fatty acids (BCFAs) that are incompatible with mitochondrial enzymes to produce some shorter acyl-CoAs [28]

Additionally, supplementation of acetylcarnitine further reduced glucose-dependent de novo lipogenesis in ACLY KO cells, suggesting that the acetyl-units provided by acetylcarnitine supplementation dilute the glucose-derived acetyl-CoA pools (Figure 6E
