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All but approximately 1 mcg is reabsorbed in patients with adequate IF

PLOS ONE 12 , e0183228 (2017)

At the ultrastructural level, irregular and immature elastin fibers and fibers devoid of microfibrils were observed. These findings suggested that both elastic fiber abnormalities and reduced collagen content contribute to the clinical features seen in patients with clEDS. There were no consistent electron microscopy (EM) findings in the ten patients in our cohort who had EM performed

[DOI] [PubMed] [Google Scholar] Karp M, Oker-Blom C

Dharmalingam et al