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Increased expression of SPARC mediates some of the exercise-induced benefits both in terms of metabolic functions, including enhancement of glucose usage and oxidative phosphorylation, as well as tissue remodeling [35]

The most widely used markers of oxidative protein damage are carbonyl compounds (aldehydes and ketones) [Marrocco et al ., 2017]

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Thalij KM, You HW, Aher KB, Bhavar GB, Kumbhar ST, Habeeb M (2025) Advances in lipid-based nanomedicine: pathway specific siRNA therapy and optimizing delivery for hepatocellular carcinoma