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4 Current asthma treatments The following two major lung barriers are typically overcome by therapeutic medications when treating lung disorders: (1) Mechanical barrier: lung disease (from an infection, for example) can produce bronchoconstriction or excessive mucus secretion, which narrows the airway

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This increase in cAMP may activate protein kinase A (PKA), which then appears to phosphorylate hormone-sensitive lipase (HSL) on specific serine sites

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