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It has been proposed that mitochondrial dysfunction and oxidative stress contribute to the incidence and progression of neurological disorders involving Alzheimers disease

If some subsets of autistic children have inherited genes, which predispose them to alcoholism, then in the absence of ethanol, they are likely to have metabolic reactions that result in an accumulation of endogenous aldehydes with similar consequences to that of acetaldehyde toxicity

Hormonal disturbances The main hormonal disturbance that leads to growth failure in CKD is GH insensitivity (described earlier)