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Recent clinical studies highlight the limited evidence supporting direct pain-modulatory mechanisms of MSC therapies 31

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all forms of marrow insufficiency, in particular with regard to the regeneration of blood cells

In ferroptotic circumstances, VDR expression diminishes

Vitamin C is a major cellular anti-oxidant, containing a highly reactive ene-diol group that transforms a relatively inactive sugar to a powerful reducing agent in aqueous solution (unlike glucose, although vitamin C is a water-soluble glucose derivative) [68]
