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On the other hand, mitochondrial OS leads to oxidized DA accumulation, ultimately resulting in reduced glucocerebrosidase enzymatic activity, lysosomal dysfunction and -synuclein accumulation in brain neurons [18]

Many studies have shown that exosomes play a crucial role in neurogenesis and are even of potential significance in treating some neurological diseases (72)

J Am Coll Cardiol 2008

The bands obtained in the synthesis of SBA-15 are in agreement with other studies reported [30, 31]

Experimental studies investigate MOTS-C for its interaction with nuclear gene expression, AMPK-associated metabolic signaling, and mitochondrial-to-nuclear communication mechanisms

doi: 10.3389/fonc.2025.1700439 Received 11 September 2025 Accepted 27 October 2025 Published 17 November 2025 Volume 15 - 2025 Edited by Zodwa Dlamini, Pan African Cancer Research Institute (PACRI), South Africa Reviewed by Yuan Qin, Xijing Hospital, The Air Force Medical University, China Hong Sun, Fudan University, China Updates Copyright 2025 Ao, Liu, Yin and Zhao