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While the exact cause of AD onset is still unclear, the prevailing hypothesis is that the increase in amyloid- (A) plaques and neurofibrillary tangles (NFTs) in the brain leads to synaptic dysfunction, and thus the onset of AD (Dias et al., 2014

This position is near the tyrosine residue that must be phosphorylated

Grandison D (Worldwide Medical Affairs, Du Pont Pharma): Personal communication

Th17 cells appear to play a role in PSC because after stimulating peripheral blood mononuclear cells (PBMCs) with C

The fusion protein (FP) of MERS-CoV binds to one Ca 2+ ion, while the SARS-CoV-2 spike (S) protein has two FP domains, FP1 and FP2, and binds to two Ca 2+ ions for host cell entry [37]

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