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Neurologists, neuroimmunologists, and neuroscientists use PET radioligands that bind to TSPO because TSPO is produced by activated microglia, the resident tissue macrophages of the central nervous system
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Thus, while both LD and HD androgens activate mTOR, only HD androgens repress c-MYC expression
The endocytosed membrane vesicles (endosomes) fuse with lysosomes, in which the apoproteins are degraded and the cholesterol esters are hydrolyzed to yield free cholesterol
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