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Conversely, the mitochondria are also a target for the damaging effect of oxygen radicals (38, 65, 109)
doi: 10.1038/nature11540 74 YeJMancusoATongXWardPSFanJRabinowitzJDet al

Brookens SK, Boothby MR

found a significant positive correlation between high amounts of aluminum and protein carbonyls, i.e., aluminum may be involved in such oxidative stress pathways [169]

2.2 Autophagy in oligodendrocytes Oligodendrocytes, the primary myelinating glia of the CNS, undergo profound structural and functional remodelling throughout their lifespan, a process driven by extensive protein synthesis, lipid production, and membrane compaction