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The primary CV endpoint is the time from randomization to the first occurrence of MACE, while the confirmatory secondary endpoints are the time from randomization to CV death and all-cause death

This increase is a notable portion of the total US prescription drug spending

What you should do: 150 minutes per week of moderate-intensity exercise, which a 2024 meta-analysis of 22 studies associated with 1218% improvement in postprandial incretin response of moderate-intensity exercise (brisk walking, cycling, swimming) plus 23 resistance training sessions

Press announcement, April 2026

Let's break down exactly what the data shows, where the side effect risks shift, and who should actually consider making the move

Acknowledgements The study was supported by the NIHR Oxford Health Biomedical Research Centre (NIHR203316) and the UKRI (MR/T033371/1 and MR/K022202)