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Accelerating drug discovery

However, multiple other neuropsychiatric disorders have been shown to involve aspects of BBB disruption, including stress disorders such as depression and anxiety [228] as well as ASD [229], epilepsy [230], and schizophrenia [231]

Hypoxia-induced stabilization of HIF-1, promote the upregulation of several pro-angiogenic genes including VEGF, FGF and PDGF [224]
