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30 Chronic stress, depression and anxiety can lead to oxidative stress, which in turn depletes glutathione

doi:10.1007/s00380-020-01698-7 Martelli A, Testai L, Colletti A, Cicero AFG

Nevertheless, several attempts have been made over the years to try to decrease the oxidative stress that plays a great part in its progression

(2019) 8:e1291

In AD, the brain endothelium releases a precursor substrate for -amyloid plaque and a neurotoxic hormone peptide that kills cortical neurons (Vagnucci and Li 2003)

The supernatant was transferred to a new tube, and the protein concentration was determined using a BCA assay (Pierce)