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Footnotes Edited by: Dawei Chen, University of Kiel, Germany Reviewed by: Eveljn Scarian, University of Pavia, Italy Hong Cheng, Yangzhou University, China Author contributions EK: Conceptualization, Data curation, Formal Analysis, Investigation, Methodology, Project administration, Resources, Software, Supervision, Validation, Visualization, Writing original draft, Writing review and editing

Thus, the DAF-12/DIN-1S complex, rather than TBH-1, induces the expression of antioxidant genes during starvation

The 3D models also predicted that the mutated FGF5 lacked the -12 strands that define the canonical trefoil of the FGF family (Fig