glp 1 neurodegenerative disease Frontiers Repurposing glucagon-like peptide-1 receptor agonists

Non-medical options like bariatric surgery may also be considered for severe obesity

For patients with well-controlled Graves disease who are euthyroid on antithyroid medications or following definitive treatment (radioactive iodine or thyroidectomy), tirzepatide may be considered if there are appropriate indications such as type 2 diabetes or obesity (BMI 30 kg/m or 27 kg/m with weight-related comorbidities)

Drug Design, Development and Therapy, 16, 44494461

Such mechanistic differences may inform future efforts to personalize GLP-1based interventions according to substance type and neurobiological profile

doi: 10.1002/oby.24336 158 Gorgojo-MartnezJJMezquita-RayaPCarretero-GmezJCastroACebrin-CuencaAde Torres-SnchezAet al

Insert the needle at a 90-degree angle in one smooth motion