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The released Fe 3+ exhausted intracellular GSH via Fenton reaction, boosting ROS production by TCPP-mediated PDT (Figures 2B, C)

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Growth factors-based therapeutic strategies and their underlying signaling mechanisms for peripheral nerve regeneration

Firstly, compared to the unstained cells (filled grey), the peak of the untreated cells (open blue) shifted to the right, indicating that all the cells have DR4 and DR5 expression on their surface ( Figure 7A )