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Having confirmed that the transfected cells expressed high levels of the desired transporters and that the transporters were indeed functional, we proceeded to use them to characterize the ability of P-gp and ABCG2 to confer resistance to FINs

10.1038/ncb3341 7

Conventional chelators such as dimercaprol (BAL), ethylenediaminetetraacetic acid (EDTA), and dimercaptosuccinic acid (DMSA) are widely used but suffer from poor selectivity, depletion of essential trace elements, and reduced efficacy in chronic exposure

doi: 10.1016/j.bbrc.2004.07.093

Challenges in monoclonal antibody-based therapies