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10.1016/S0140-6736(10)60888-4 [EL 1

A high-fat diet increases the expression of lipid synthesis and transport proteins while increasing inflammation and oxidative stress damage

They also act on the appetite centers in the brain, significantly reducing hunger and what is often called food noise. The dual-action drug tirzepatide works on both GLP-1 and GIP receptors, often leading to even greater efficacy

Strut Health has recieved some very positive reviews from people who have tried it

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Since GLP-1s can cause side effects such as nausea, diarrhea and constipation, it is best to limit excess fat and sugar in foods and beverages, as they can intensify these symptoms, say Feldman and Dalyai