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Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a singlecenter, prospective, randomized, openlabel study

Objective markers (IGF-1, metabolic panels, and where tested, biological age) typically show measurable improvement

The hypothesis is that by combining these two agents, one addresses the systemic hormonal signals that govern eating behavior and macroscopic energy balance, while the other fine- tunes the cellular machinery responsible for metabolic efficiency

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[DOI] [PubMed] [Google Scholar] 13.Gosens T, Peerbooms JC, van Laar W, den Oudsten BL

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