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1 Astressin 2B TFA is a blood-brain barrier-impermeable, highly selective CRFR2 antagonist ( rCRFR2 , IC 50 =0.57 nM)

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DOI:10.1016/s0006-2952(02)01176-0

Subsequently, tyrosines 1349 and 1356 in the carboxy-terminal tail become phosphorylated

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