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10.1155/2012/986519 [DOI] [PMC free article] [PubMed] [Google Scholar] 23.Hardan AY, Fung LK, Libove RA, Obukhanych TV, Nair S, Herzenberg LA, et al

Imaging examinations, such as low-dose computed tomography (LDCT), are the most direct means of early screening, but they are limited by a high rate of false positives, significant radiation exposure, and insufficient sensitivity to detect small lesions, thereby constraining the effectiveness of early screening

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