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Several studies indicate positive results with dosage between 250-300mg daily, but in some cases, high doses might be required

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Ideally, the targeted receptor- or carrier-mediated transport processes for brain targeting should occur exclusively at the BBB to avoid off-target delivery

Physical hydrogels are simple to produce and have low cytotoxicity, but they frequently become unstable in physiological settings and do not immediately react (Khan et al., 2022

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Fe 2+ induced iron accumulation, oxidative damage and autofluorescence of photoreceptors, resulting in photoreceptor death and RPE autofluorescence in mouse models (Shu et al., 2020)