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More broadly, these findings show that by buffering toxic lipids and sequestering selected drugs, the metabolic plasticity provided by LD remodeling supports cancer cell survival under treatment stress and leads to therapy resistance

Enzymatic methods were used to measure serum concentrations of triglycerides, total cholesterol, and HDL-C on the Cobas 6000 c501 analyzers (Roche Diagnostic GmbH, Mannheim, Germany), with HDL-C assessed after the combination of non-HDL lipoproteins with polyanions and a detergent

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doi: 10.1016/j.devcel.2008.01.019 Rasmussen, J.P., Feldman, J.L., Somashekar, S

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