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30 Instead, off-target proteins like glutathione S -transferase omega-1, heme oxygenase 2, and thioredoxin domain containing 17 protein were identified
10.1158/1940-6207.Capr-20-0123 [DOI] [PubMed] [Google Scholar] Cho S

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In contrast, deletion or inhibition of GPX4 causes rapid H 2 O 2 accumulation and RIPK3-mediated necrosome activation 72,73