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Nanoparticles can be passively targeted to cancer cells through the improved permeability and retention effect in tumor tissues after being entered into blood arteries while being rejected as foreign substances by mononuclear macrophages [172]
This is one of the most practically significant differences between SMART removal and conventional drilling

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Stanford EJ, Mattox TF, Parsons JK et al: Prevalence of benign microscopic hematuria among women with interstitial cystitis: Implications for evaluation of genitourinary malignancy
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Outcomes of patients with oropharyngeal squamous cell carcinoma treated with induction chemotherapy followed by concurrent chemoradiation compared with those treated with concurrent chemoradiation
