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Abnormal neutrophil recruitment in CF airways increases oxidative stress, causing redox imbalance and elastase/IL-8 release

Dimethyl sulfoxide (DMSO) is a particularly well-known sulfoxide that is often used as a polar aprotic solvent

In addition, a flavonoid called kaempferol possesses many biological activities such as cardio-protective, anti-inflammatory, anti-allergic, antidiabetic, osteoporotic, and analgesic (143, 151)

[DOI] [PubMed] [Google Scholar] 86.Wu A, Ying Z, Schubert D, Gomez-Pinilla F

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Studies conducted on cultured cell lines revealed that Tamoxifens increase of endogenous Cer levels (an estrogen receptor antagonist used widely in breast cancer) promoted autophagy-associated cell death, which theoretically synergizes with its anti-tumor action [68]
