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Intratympanic Steroid Injection

Am J Physiol Gastrointest Liver Physiol (2020) 318(3):G43950

This antitumorigenic effect is mediated through the activation of cyclin-dependent kinase inhibitors specifically p21 & p27, which disrupt the action of mitogenic growth factors such as insulin-like growth factor 1 (IGF-1) and epidermal growth factor (EGF), while simultaneously enhancing the tumour-suppressive effects of transforming growth factor-beta (TGF-)

doi:10.1136/bmj.2.5351.225

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It is a dual agonist that activates both the GLP-1 and GIP (glucose-dependent insulinotropic polypeptide) receptors
