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Additionally, data suggest that the reduced NF-B, p65 DNA binding activity was the cause of the attenuated inflammatory response with lutein therapy

303 Other activities In addition to the above-listed activities, Jamun has been shown to possess anticoagulant, anti-aging, antimalarial and antiasthmatic properties

[DOI] [PMC free article] [PubMed] [Google Scholar] 350.Murakami Y., Ikeda Y., Yoshida N., Notomi S., Hisatomi T., Oka S., et al

For instance, curcumin demonstrates significant anti-inflammatory effects by inhibiting NF-B activation and reducing the expression of COX-2, IL-1, and TNF-

Nature 575 , 512518 (2019)

VacA caused the translocation of cytoplasmic BAX to mitochondria and increased cytochrome c to facilitate apoptosis, while the expression of cellular apoptosis inhibitory protein (c-IAP)-2 was upregulated in the early phase of VacA stimulation (Kim et al., 2010)