isothiocyanate glutathione Isothiocyanates as H2S Donors Triggered by Cysteine: Reaction Mechanism and Structure and Activity Relationship Phenethyl isothiocyanate | CAS 2257-09-2

D.LeighR.et al (2013)

Background Glutathione is a tripeptide found in various foods and beverages, including grape must and wine, in its reduced (GSH) or oxidized (GSSG) states Saccharomyces cerevisiae and/or non- Saccharomyces yeasts

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The three cysteines outside the active site (C8, C79, C83) are also vulnerable to oxidation, and both intra- and inter-molecular disulfide bond formation have been reported 8,23,24,25

Peptides: 4

A role for glutathione as a glutamate reservoir may be a bridge between distinct lines of research that implicate glutamatergic dysfunction and aberrant glutathione levels in neuropsychiatric conditions such as schizophrenia