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The therapeutic strategy mentioned in the text involves targeting immune organs to counteract immunosenescence by restoring thymic vitality, rejuvenating bone marrow niches, and improving the function of peripheral immune organs, ultimately enhancing the generation and functionality of immune cells

In osteoarticular diseases, MSCs synergize with biomaterial scaffolds to enhance cartilage regeneration, whereas in cardiovascular repair, their angiogenic potential improves cardiac function post-myocardial infarction

It seems to lower calcium and phosphate concentration in the blood

Studies have found that long-term high-fat diet significantly activates the NF-B signaling pathway, manifested as increased hepatic p-IB and p-p65 protein levels, and markedly elevated expression of pro-inflammatory factors TNF- and IL-1 in serum and liver tissue [38]

AMP-activated protein kinase (AMPK) senses cellular energy levels and is activated when energy levels are low, which serves to reduce ATP consumption and promote ATP production

I., Flax, J