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It primarily acts on core targets such as epidermal growth factor receptor, intercellular adhesion molecule 1, nuclear factor kappa B subunit 1, prostaglandin-endoperoxide synthase 2, and signal transducer and activator of transcription 3 to modulate the hypoxia-inducible factor-1, tumor necrosis factor, and nuclear factor kappa B signaling pathways

Current reliance on preclinical evidence underscores the urgent need for rigorous clinical trials

[DOI] [PMC free article] [PubMed] [Google Scholar] 74.Noguchi S

The values for total glutathione were 1.377 0.0021 mg g 1 , 0.543 0.0047 mg g 1 , and 0.355 0.0121 mg g 1 wet weight for the hepatopancreas of C

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A large number of epidemiologic studies have reported the protective effects of dietary antioxidants such as micronutrients vitamin A, C, and E, polyphenol, and carotenoids against the development of asthma and decline of lung function