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In general, the disease onset tends to present with an acute active inflammatory phase, characterized by pain during erection and penile curvature progression, leading to chronic stable fibrotic phase at which the pain tends to disappear and penile curvature becomes stable [7]

Despite the lack of further confirmation, 17-estradiol, adenosine receptor A2B agonist, and ROCK inhibitor have shown to be effective for acute PD

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st July 2026
