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Down-regulation of CFL1 or decreased CFL1 phosphorylation can alleviate erastin-induced HT22 cell death and reduce the glutamate-induced excitotoxicity of primary cortical neurons [135]

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Following this, for every individual subject, the placement of the MRS voxel was applied as a 20 20 20 mask (individually measured for each subject based on 1H-MRS acquisition) to the three respective tissue maps providing a segmentation quantity for each tissue in the specific 1H-MRS voxel placement

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