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Cortisol, a glucocorticoid hormone, is known to have neurotoxic effects when present in excess

While the NARP embryos tended to have either 95% mutant mtDNAs, the MELAS embryos harbored a wide range of heteroplasmy levels from 0% to 80%

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Samples were mixed with loading buffer prior to electrophoresis and loaded onto either (i) a 16% denaturing polyacrylamide gel (prepared in TBE buffer with 20% formamide), where an aliquot of the reaction mixture was mixed with an equal volume of loading buffer and electrophoresed at 500 V for 90100 min at room temperature, or (ii) a 15% Novex TBE Urea Gel (Thermo Fisher Scientific), where 1 L of the reaction mixture was mixed with 9 L of loading buffer and electrophoresed at 200 V for 8090 min

aureus has also been shown to be involved in spreading of the bacteria into both lobes of rabbit lungs and can cleave the tethered MUC16 off CALU3 epithelial cells (Paharik et al., 2016)