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CagriSema also produced significant improvements in systolic blood pressure (a 10.9 mmHg reduction), along with improvements in lipids and inflammatory markers

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In parallel to the plasma membrane-localized FSP1 system, a distinct, mitochondria-specific antioxidant axis that counteracts ferroptosis centered on the enzyme dihydroorotate dehydrogenase (DHODH) has been identified (36)
