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Mitochondrial dysfunction and insulin resistance: an update

Cell Metab 7: 9596, 2008

Although both models aimed to simulate human MASLD, CDHCD did not replicate obesity-associated insulin resistance, as indicated by the unchanged HOMA-IR, whereas CDHFHCD model disrupted energy homeostasis via impairing thermogenesis and attenuating adipokine signaling, which was distinct from the metabolic processes observed in human MASLD

A trail of rattled Floridian female gym-goers

N2 in N2 male condition: 11.72 0.28 days, n = 97 worms
