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Thus, the loss of intracellular GSH in the presence of active generation of hydroperoxy-phospholipids could occur through several active mechanisms, including formation of GSH, export of GSSG, inadequate replenishment of GSH, or insufficient levels of GSSG reductase, each directly or indirectly dependent on the generation of hydroperoxy-phospholipids

In addition, growth of the control seedlings was accelerated by GSSG treatment and decreased by GSH or other sulfhydryl reducing agents

On the other hand, very high enzyme values combined with vomiting, jaundice, poor appetite, or neurological changes may indicate more significant liver disease that requires immediate veterinary attention

Medications Several commonly prescribed medications can temporarily increase liver enzyme levels without causing permanent liver disease

90 : 12591266 Filomeni G, Rotilio G and Ciriolo MR (2003) Glutathione disulfide induces apoptosis in U937 cells by a redox-mediated p38 MAP kinase pathway

[DOI] [PMC free article] [PubMed] [Google Scholar] 68.Saylam B, ayan S