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doi: 10.1007/s10456-007-9074-0

On exposure to light, it gradually darkens

Elevated plasma homocysteine levels are linked to atherogenesis 106 and subsequently to endothelial dysfunction

Cell Metab 36(2):354376

Whether declining MOTS-c is a cause or consequence of this deterioration is still being resolved, but the correlation is striking enough that some researchers have proposed plasma MOTS-c as a biomarker of mitochondrial vitality and metabolic age

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